Inogen One G5 vs. Respironics SimplyGo Concentrator Comparison

There are two types of portable oxygen concentrators (POCs) available on the market today: continuous flow oxygen and pulse dose, or intermittent flow, oxygen concentrators. The type of unit and flow settings you’ll need will be determined by your doctor. But it’s up to you to choose an oxygen concentrator that will best suit your needs and lifestyle.

We’ve compared two industry-leading portable oxygen concentrators, the Respironics SimplyGo and the Inogen One G5, to help you determine which machine is best for you.

Inogen One G5 vs. Respironics SimplyGo Flow Settings

The Inogen One G5 is a pulse dose oxygen delivery system that provides gentle bursts of oxygen whenever you breathe. The G5 offers six different pulse settings and features Inogen’s Intelligent Delivery Technology which ensures oxygen is delivered within the first 400 milliseconds of inspiration, when oxygen is most effective. It also adapts to your oxygen needs as your breathing changes, like at night; it’s designed to deliver more oxygen per breath as the frequency and depth of respiration decreases during sleep.

The Respironics SimplyGo has both continuous flow and pulse dose capabilities. This portable oxygen concentrator system has six different pulse output settings and delivers up to 2 LPM on the continuous flow setting. The SimplyGo also features a Sleep Mode setting that increases oxygen output during the night.

Weight and Size

The Inogen One G5 is one of the most portable and lightweight POCs available, weighing in at 4.5 pounds and measuring 8 inches tall, 7 inches long, and about 3 inches deep. It comes with a carry bag that you can easily carry over your shoulder.

The SimplyGo is also an easily transported concentrator, though larger than the G5. It weighs 10 pounds and measures 10 inches tall, 11.5 inches long, and 6 inches deep. It comes with a carrying case, detachable accessory bag, and a cart.

Inogen One G5 vs. Respironics SimplyGo Portable Oxygen Concentrator

Battery Life

It’s crucial you consider battery life and charging time when evaluating and choosing the right portable oxygen concentrator for you. You need the battery life of your POC to match your routine, needs, and lifestyle.

The battery life for the Respironics SimplyGo will depend on whether you’re using it as continuous flow (1.6 hours at 1 LPM) or pulse delivery (3 hours), as well as what setting it’s on.

The Inogen One G5 boasts the longest battery life of any POC on the market today. The exact length will depend on which pulse dose setting and battery (8-cell single or 16-cell double) are being used. The G5 can last up to 6.5 hours with the single battery and 13 hours with the double battery on a setting of 2.

Inogen One G5 Battery Life and Power Power Consumption:

Inogen One G5 Battery Life and Power Power Consumption

*Battery run times are based on average values. Actual run times may vary up to 10%.

Side-by-Side Unit Comparison

*includes single battery
Width: 7.19 inches
Depth: 3.26 inches
Height: 8.15 inches
Width: 11.5 inches
Depth: 6 inches
Height: 10 inches

4.7 pounds
10 pounds

Oxygen Settings
Continuous Flow: Not supported
Pulse Dose: 1 to 6 settings
Continuous Flow: 0.5 to 2 in 0.5 increments
Pulse Dose: 1 to 6 settings

Battery Duration
Up to 4.5 hours with single battery
Up to 9 hours with double battery
Pulse: 3.4 hours
Continuous: 1.6 hours (at 1 LPM setting)

Battery Charging Time
Approximately 2-4 hours for single battery
About 2 to 3 hours from 0% charge to 100%

Noise Level
Around 38 decibels on a setting of 2
Around 43 decibels at a setting of 2

Maximum Oxygen Output
1260 ml/min
2000 ml/min

FAA Approved

3 Year Warranty on Unit, 90 Day Warranty on Accessories
3 Year Warranty on Unit, One Warranty on Accessories

Additional Features

Additional features to note for the Inogen One G5 include:

  • An easy-to-read LCD display
  • Simple, intuitive controls
  • It is Bluetooth capable and fully integrated with the Inogen Connect App

Additional features to note for the Respironics SimplyGo include:

  • Its durable compressor was created to last for years
  • It can function at altitudes of up to 10,000 feet
  • There are alarms built into the device for low oxygen purity, high breath rate, no breath detection, no flow, depleted battery, and more.

The Final Choice: Inogen One G5 vs. Respironics SimplyGo

Whether the SimplyGo or Inogen One G5 is the right oxygen concentrator for you will depend on the type of concentrator you need, as well as the level of portability you’re looking for.

Do you need continuous flow or pulse dose? Do you want to carry your POC on your shoulder, wear it in a backpack, or pull it on a cart? Do you need a concentrator to bring on errand runs or bike rides and hikes? How lightweight do you need your POC to be?

The answers to these questions, along with your doctor’s advice, will help you choose the right portable oxygen concentrator for you.

Have more questions about for these units?

About Scott Ridl: Scott joined American Medical Sales and Rentals in 2008 as a Web Manager and Content Writer. He is a writer and designer. He is extensively trained on oxygen therapy products from leading manufacturers such as Inogen, Respironics, Chart, Invacare, ResMed and more. Scott works closely with respiratory therapists and oxygen specialists to educate the community about oxygen therapy products, COPD, asthma and lung diseases. He writes weekly columns and is passionate about educating the community on oxygen therapy and respiratory issues.

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