A Comparative Pilot Study of Three Portable Oxygen Concentrators

A Comparative Pilot Study of the Efficacy of Three Portable Oxygen Concentrators during a 6-minute Walk Test in Patients with Chronic Lung Disease.

Rationale: While use of portable oxygen concentrators (POC) is likely to increase, research is limited on the ability of POC’s to maintain oxygen saturation ≥ 90% during exercise.

Objective: To compare the efficacy of 3 POC’s, with the highest O2 capacity in maintaining exertional O2 saturations ≥ 90% in patients with Chronic Obstructive Pulmonary Disease (COPD) or Pulmonary Fibrosis (PF).

Methods: Patients who were O2 dependent and within 2 years post pulmonary rehabilitation were invited to participate.

Inclusion criteria

Medically stable
R/A exertional
Desaturation ≤ 85%

Exclusions criteria
Require .6 L/min of oxygen
Conditions limiting walking ability
Significant cognitive or memory deficit

Six minute walk tests (6_MWTs) were administered, monitoring pulse oximetry (Sp02) . A control 6-MWT was performed with the participants’ current 02 system and prescribed exercise flow rate. A cross over design was used. Participants randomly performed a 6-MWT with each of the 3 POCs at the max pulse dose setting and stopped if their SP02 was ≤ 85%. A self admin, questionnaire was completed after each walk.

Study POCS

No financial support was received from the manufactures/distributors.

Results: Ten participants (5 male, 5 female, average 67.1 +/- 7.6 years old.) were included (9 COPD, 1PF). On average, the Eclipse 3 resulted in the highest Sp02 at each time point and corresponded with increased total time and total distance walked. Significant differences in Sp02 excisted between the Eclipse 3 and all other POCs ( p <0.05).

Sp02 before and after 6-MWT



Questionnaire Responses

Conclusions: All POCs increased Sp02 during exertional walk but only the Eclipse 3 resulted in mean SPo2 ≥ 90%.

References:
1. McCoy R Petty T, Gay P. Comparison of three portable oxygen concentrators on exercising patients [White Paper]. Respironics, April 2008
2. Nasilowski J, Przybylowski T, Zeilinkski, J, Chazan R. Comparing supplementary oxygen benefits from a portable oxygen concentrator and liquid oxygen portable device during a walk test in COPD patients on long-term oxygen therapy. Resp Med 2008; 102: 1021.
3. Strickland S L, Hogan M T, Hogan R g et al. A randomized multi-arm repeated - measure prospective study of several modalities of portable oxygen delivery during assessment of functional exercise capacity. Respir Care 2009; 54 (no 3): 344
4. Enright PL, Sherrill DL. Reference Equations for the Six Minute Walk in Healthy Adults. Am J Respir Crit Care Med 1998; 158: 1384-1987

About Scott Ridl: Scott joined American Medical Sales and Rentals in 2008 as a Web Manager and Content Writer. He is a writer and designer. He is extensively trained on oxygen therapy products from leading manufacturers such as Inogen, Respironics, Chart, Invacare, ResMed and more. Scott works closely with respiratory therapists and oxygen specialists to educate the community about oxygen therapy products, COPD, asthma and lung diseases. He writes weekly columns and is passionate about educating the community on oxygen therapy and respiratory issues.

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